1. Duty origin

The design is for the production line of 5-fluoro-2,3-dihydrogenbenzofuran with an annual output of 30 tons, and the design of the workshop and the preparation of product requirements document. The production of 5-fluorophenol-2,3-dihydrobenzofurans is based on the three-step reaction of bromination section, alkylation section and alkylation in the molecule.

The design content is calculated according to the existing brominatio section, alkylation section, molecular alkylation, and then energy balance on the results of material balance calculation, in addition, the equipment selection of the main equipment involved in bromination , alkylation, and alkylation of the molecule, according to the selected equipment, the workshop layout. The CAD software is used to draw the layout chart of the workshop equipment, the assembly diagram of the reactor and the flowchart of the process. Finally, summarize the highlights and weaknesses in the design and thank the instructor.

2. Design standard

This design has referred to below the national standard and the stipulation.

a. Production process dangerous material and harmful factor classification and code. (GB/T13816-1992)

b. Commonly used dangerous chemistry classified standard. (GB13690-1992)

c. In pressure vessel chemistry medium model harm and explosion hazard degree classification. (HGJ43-1991)

d. Factory fire protection stipulation. (GBJ16-1987)

e. The sewage synthesis discharges the stipulation. (GBJ8978)

f. The steel pins down the pressure vessel. (GB150)

g. Shell type heat interchanger standard. (GB151)

h. Craft system arrangement of equipment design stipulation. (HG20570)

i. Chemical installment piping arrangement design stipulation. (HG/T20549)

3. Principle of design and main design standard

Principle:

(1) Safety: A lot of substances in chemical production are inflammable, explosive or toxic. Therefore, the design must take full account of the obvious and potential dangers and ensure the health and safety of the production staff.

(2) Ease of operation: The operation conditions should be determined rationally while determining the various production processes and equipment. Because of its direct relation to the establishment of production process and equipment and the development of its function and the determination of the control programme.

(3) Economics: Namely the request economically uses the equipment investment, the construction invests, the public project investment and the manpower cost.

(4) Is advantageous for the installment: Factory layout shall meet the requirements for construction and installation operations. In particular, the lifting of large equipment should be considered, and the pavement structure and load standard of the road in the factory should meet the requirements of construction installation.

Key words： 5-fluoro-2,3-dihydroisobenzofuran ; 4-fluorophenol ; process design; reactor

目 录

1 概述 1

1.1 设计项目名称 1

1.2 生产规模 1

1.3产品说明 1

1.4原料及中间体的主要用途、理化性质、规格 1

1.5 设计依据 7

2 生产车间工艺流程设计 8

2.1生产工艺的选择 8

2.2 物料流程框图 8

2.3 各工段产品指标 10

3 生产车间工艺计算 11

3.1 物料平衡计算 12

3.1.1 投料计算 12

3.1.2 溴化反应物料衡算 12

3.1.3 烷基化反应物料衡算 15

3.1.4 分子内烷基化反应物料衡算 18

3.1.5 总物料衡算 20

3.2 热量衡算 20

3.2.1 溴化反应热量衡算 21

3.2.2 烷基化反应热量衡算 29

3.2.3 分子内烷基化反应热量衡算 34

4 部分设备的选型和计算 40

4.1 溴化釜的设备计算 40

4.2 烷基化反应釜的设备计算 40

4.3 分子间烷基化釜的设备计算 41

4.4 部分设备的选型 42

4.5 设备一览表 46

5 行政法规执行措施 47

5.1 消防设计说明 47