摘要：利用光纤探针将激光精确地引入人体组织，使得人体组织中的胶原和蛋白与激光发生相互作用，使切口相互吻合，这种技术称为激光焊接生物组织。1970年前后，Klink等对于生物组织激光焊接的成功拉开了激光焊接生物组织的序幕，并且由此显示出了其独特的优越性使得越来越多的研究者投身到了激光焊接的研究中，并在生物组织选择上进行推广。激光焊接法以其吻合速度快、愈合过程无异物反应、保持焊接部位的原有力学性质等优点，显示出了与传统缝合方法相比的优越性，将在未来的生物科学与临床医疗上有更全面的应用。本文以生物组织皮肤特性和光学效应为出发点，基于生物组织的热学与光学理论知识，采用“正交试验设计”的方法，通过试验探讨了不同牛血清蛋白溶液浓度及色素添加剂种类对皮肤切口焊后吻合效果的影响规律，提出了参数的最优方案，目的是为了提高手术效率和安全性打下理论基础。

关键词  激光焊接生物组织  BSA  色素添加剂

毕业设计说明书外文摘要

Title  Experimental Study of the biological under laser welding flux action BSA  

Abstract：The use of fiber optic probes to accurately introduce laser into human tissue，through the organization of the absorption of the laser，interact to generate heat effect，so that the incision organization to achieve the purpose of mutual integration，This technique is called laser welding of biological tissue。Laser welding biological tissue began in the 1970s，Klink and Jain et success by laser welding oviduct and blood vessels，and show the superiority, prompting more and more researchers to explore the welding of various biological tissue, and in the selection of biological organizations to promote。To Compare with the method of traditional suture, the laser welding method has the advantages of fast coincidence, healing process without foreign body reaction, and maintain the mechanical properties of the welding site, the repair organization according to its original bio-mechanical characteristics of growth, etc., will be in the future of biological Medicine has been more widely used。Based on the biological properties and optical thermal effects of biological tissue, the effects of different bovine serum albumin solution concentration and pigment additive on the skin incision were studied by means of orthogonal test design. Anastomosis effect of the law, proposed the optimal parameters of the program, the purpose is to improve the efficiency and safety of surgery to lay the theoretical basis.

Keywords  Laser Welding Biological Tissue  BSA  Pigment Additive

目   次

1 绪论 1

  1.1 生物组织激光焊接原理 1

    1.1.1 激光焊接原理 1

    1.1.2 生物组织激光焊接技术应用 2

  1.2 生物组织激光焊接研究现状 3

    1.2.1 国外研究现状 3

    1.2.2 国内研究现状 4

  1.3 主要研究内容及方法 4

    1.3.1 主要研究内容 4

    1.3.2 研究方法 4

2 生物组织特点 4

  2.1 皮肤结构 4

  2.2 生物组织的光学特性 4

    2.2.1 反射和折射 4

    2.2.2 吸收 5

    2.2.3 散射 7

    2.2.4 透射 7

    2.2.5 小结 7

3 色素的选择及光学性质 9

3.1 吸收光谱原理 9

3.2 天然色素 9

    3.2.1 叶绿素的光学特性 9

    3.2.2  β-胡萝卜素的光学特性 10

3.3 人工合成食用色素 11

    3.3.1 人工合成日落黄的光学特性 11

    3.3.2 人工合成苋菜红的光学特性 11

    3.3.3 人工合成亮蓝色的光学特性 11